Production of the super catalytic antibody inhibiting the pandemic of influenza virus

2015 Fiscal Year Final Research Report

• Project/Area Number: 24350085
• Research Category: Grant-in-Aid for Scientific Research (B)
• Allocation Type: Partial Multi-year Fund
• Section: 一般
• Research Field: Chemistry related to living body
• Research Institution: Oita University
• Principal Investigator: HIFUMI EMI 大分大学, 全学研究推進機構, 教授 (90254606)
• Project Period (FY): 2012-04-01 – 2016-03-31
• Keywords: 抗体酵素 / インフルエンザウィルス / 抗体軽鎖 / 構造多様性

Outline of Final Research Achievements

We have carried out to develop several items such as production method, purification method, enzymatic function, anti influenza activity of super catalytic antibody in accordance with the schedule planned in the application form. We have made a huge development in the production method as well as the anti influenza function of human catalytic antibody. Regarding the structural diversity of catalytic antibody, we have discovered the novel method to solve the difficult and long-term issue on diversity.

Free Research Field

バイオテクノロジー、抗体工学