Yeast Phenome analysis with super-hidimensional morphological profiling

2014 Fiscal Year Final Research Report

• Project/Area Number: 24370002
• Research Category: Grant-in-Aid for Scientific Research (B)
• Allocation Type: Partial Multi-year Fund
• Section: 一般
• Research Field: Genetics/Genome dynamics
• Research Institution: The University of Tokyo
• Principal Investigator: OHYA Yoshikazu 東京大学, 新領域創成科学研究科, 教授 (20183767)
• Project Period (FY): 2012-04-01 – 2015-03-31
• Keywords: 出芽酵母 / 表現型解析

Outline of Final Research Achievements

The primary goal of automated morphological analysis of subcellular structures using image extraction and quantification is to ensure objectivity and reproducibility. A well-designed experiment followed by appropriate statistical analyses can provide a wealth of biologically meaningful information. With regard to budding yeast, it is essential to quantitatively study the phenotype of numerous sets of mutants to extract genetically and biologically meaningful information. In this study, we addressed some of the biological findings to which quantitative morphological analysis has contributed significantly.

Free Research Field

分子生物学