Review and analysis of mechanism for noise-induced deafness by epidemiological and experimental studies

2015 Fiscal Year Final Research Report

• Project/Area Number: 24390157
• Research Category: Grant-in-Aid for Scientific Research (B)
• Allocation Type: Partial Multi-year Fund
• Section: 一般
• Research Field: Hygiene
• Research Institution: Nagoya University
• Principal Investigator: Kato Masashi 名古屋大学, 医学(系)研究科(研究院), 教授 (10281073)
• Co-Investigator(Kenkyū-buntansha): OHGAMI Nobutaka 名古屋大学, 大学院医学系研究科, 講師 (80424919) ; YAJIMA Ichiro 名古屋大学, 大学院医学系研究科, 講師 (80469022) ; YAMANOSHITA Osamu 中部大学, 生命健康科学部, 講師 (50424924)
• Project Period (FY): 2012-04-01 – 2016-03-31
• Keywords: 難聴 / 環境因子 / 騒音

Outline of Final Research Achievements

Our epidemiological study in limited number of subjects showed significant correlation between hearing level of 8k Hz and smoking and barium concentration in toenail but not sound level from personal music players at present moment. We will keep analyzing the correlation between hearing level and sound level from personal music players with increasing the number of subjects. Our experimental study further identified candidates of preventive medicines as well as regulatory molecules for noise-induced deafness. Our experimental study also showed promoted hearing loss in mice by drinking barium. Thus, we provided new insight for environmental factors-mediated deafness by our epidemiological and experimental studies.

Free Research Field

衛生学・耳科学