Study on effectiveness of denture adhesives: Multi center prospective clinical trial for clinical guidline

2014 Fiscal Year Final Research Report

• Project/Area Number: 24390439
• Research Category: Grant-in-Aid for Scientific Research (B)
• Allocation Type: Partial Multi-year Fund
• Section: 一般
• Research Field: Prosthetic dentistry
• Research Institution: Nihon University
• Principal Investigator: KAWAI Yasuhiko 日本大学, 松戸歯学部, 教授 (50221198)
• Co-Investigator(Kenkyū-buntansha): KIMOTO Suguru 日本大学, 松戸歯学部, 講師 (10267106) ; ICHIKAWA Tetsuo 徳島大学, ヘルスバイオサイエンス研究部, 教授 (90193432) ; KIMOTO Katsuhiko 神奈川歯科大学, 歯学部, 教授 (70205011) ; SUZUKI Tetsuya 東京医科歯科大学, 歯学部, 教授 (60179231) ; HONG Guang 東北大学, 歯学研究科, 助教 (70363083) ; HAMADA Taizou 東北大学, 歯学研究科, 教授 (50034244) ; MURATA Hiroshi 長崎大学, 医歯(薬)学総合研究科 (40229993) ; MINAKUCHI Shunsuke 東京医科歯科大学, 医歯(薬)学総合研究科, 教授 (30219688) ; YONEYAMA Yoshikazu 鶴見大学, 歯学部, 助教 (50230842) ; OKAZAKI Joji 大阪歯科大学, 歯学部, 教授 (80169094)
• Project Period (FY): 2012-04-01 – 2015-03-31
• Keywords: 義歯安定剤 / 多施設研究 / 無作為割付臨床試験 / ガイドライン / 臨床エビデンス

Outline of Final Research Achievements

To investigate the efficacy of denture adhesives, randomized controlled clinical trial was carried out in ten multi-center institutions. As an intermediate result, no significant difference has been observed between the experimental groups and control group, in terms of objective and subjective outcomes. The trial targeted 300subjects as sample size and yet 49% has been achieved. The lack of statistical power may have affect the intermediate results.

Free Research Field

歯科補綴学