Development of non-invasive near-infrared assessment system for intrauterine fetal well-being

2014 Fiscal Year Final Research Report

• Project/Area Number: 24500540
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Medical systems
• Research Institution: Kanazawa University
• Principal Investigator: NOGAWA Masamichi 金沢大学, 機械工学系, 助教 (40292445)
• Co-Investigator(Kenkyū-buntansha): UCHIDE Kiyoshi 金沢大学, 医学系, 協力研究員 (00168709) ; OGAWA Mitsuhiro 帝京大学, 理工学部, 講師 (30322085) ; TANAKA Shinobu 金沢大学, 機械工学系, 教授 (40242218) ; YAMAKOSHI Ken-ichi 昭和大学, 医学部, 客員教授 (40014310)
• Project Period (FY): 2012-04-01 – 2015-03-31
• Keywords: 胎児血中酸素飽和度 / パルスオキシメータ / 放射輸送方程式 / 光拡散方程式

Outline of Final Research Achievements

Toward a development of non-invasive near-infrared assessment system for intrauterine fetal well-being, we have evaluated the performance of the proposed system, which offers non-invasive transabdominal measurement of fetal arterial oxygen saturation, with pregnant women in regular prenatal care.
The proposed system consists of three major parts: a two-wavelength transabdominal fetal photo-plethysmography (750/830nm), frequency domain signal extraction procedure of fetal plethysmogram from transabdominal photo-plethysmogram, and non-blood drawing sensor calibration procedure based on radiative transfer for safe and reliable non-invasive fetal arterial oxygen saturation measurement.
As a result of the clinical trials, the non-invasive fetal assessment system could offer acceptable normal arterial oxygen saturation ranges of intrauterine fetuses: 50-70%.

Free Research Field

医用システム