Elucidation of enhanced process in aging central nerve by the running and balance exercise

2014 Fiscal Year Final Research Report

• Project/Area Number: 24500598
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Rehabilitation science/Welfare engineering
• Research Institution: Saitama Prefectural University
• Principal Investigator: KANEMURA Naohiko 埼玉県立大学, 保健医療福祉学部, 准教授 (20379895)
• Co-Investigator(Kenkyū-buntansha): TAKAYANAGI Kiyomi 埼玉県立大学, 保健医療福祉学部, 教授 (20274061)
• Co-Investigator(Renkei-kenkyūsha): IMAGITA Hidetaka 畿央大学, 健康科学部, 教授 (00412148) ; MORIYAMA Hideki 神戸大学大学院, 保健学研究科, 教授 (10438111) ; MAEJIMA Hiroshi 北海道大学院, 保健学研究院, 教授 (60314746)
• Project Period (FY): 2012-04-01 – 2015-03-31
• Keywords: 老化 / 走行運動 / バランス運動 / 中枢神経可塑性

Outline of Final Research Achievements

Moderate exercise, the release of neurotrophic factors is increased , neural activity is activated. In this study, whether it is possible to activate the nervous system that has been decreased by aging and to verify the effect of the running and balance exercise. Activation of the motor neurons stained of the lumbar spinal cord was less change in some exercise. Their expression of neurotrophins, neurogenesis and neurpeptide were enhanced and the activity of apotosis wad down-regulated by locomotor exercise in the spinal cord of the difference of age. Improvements due to the motion, not the nerve itself, it is necessary to consider in the pleiotropic functions for related factors activated neural activity.

Free Research Field

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