The effect of local heating to the exercising muscle in interleukin-6 release from the muscle.

2015 Fiscal Year Final Research Report

• Project/Area Number: 24500605
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Rehabilitation science/Welfare engineering
• Research Institution: Kyoto Prefectural University of Medicine (2015); Wakayama Medical University (2012-2014)
• Principal Investigator: ITO TOMOYUKI 京都府立医科大学, 医学(系)研究科(研究院), 助教 (90305566)
• Co-Investigator(Kenkyū-buntansha): YOSHIDA TAKAKI 関西医療大学, 保健医療学部, 講師 (60454659)
• Project Period (FY): 2012-04-01 – 2016-03-31
• Keywords: インターロイキン６ / 局所温熱 / 運動 / ノルアドレナリン / 体温

Outline of Final Research Achievements

We examined plasma interleukin-6 (IL-6) response during and after exercise with local heating to contracted skeletal muscle in seven healthy subjects. IL-6 response to local heating in exercise without heating (EX condition), exercise with local heating (HEX condition), and resting with local heating (H condition) were measured. Subject exercised at 60% of VO2max for 30min in EX and HEX, 30min of resting in H condition. Simultaneously, both thigh was warmed by the electric pads for 30 min in HEX and H. Plasma IL-6 increased in HEX after exercise. Local heating without exercise also increased IL-6 2 hours after heating. The examination made it clear that plasma IL-6 response is up-regulated by local heating to skeletal muscle during exercise.
We also examined the effect of 10 weeks exercise training with local heating to response of IL-6 during exercise in 4 subjects. Response of IL-6 during exercise with local heating to exercising muscle did not change after training.

Free Research Field

運動生理学