2015 Fiscal Year Final Research Report
Expression analysis of circadian genes in mouse liver exposed to ionizing radiation
| Project/Area Number |
24510062
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Risk sciences of radiation/Chemicals
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| Research Institution | Tohoku University |
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Principal Investigator |
Uehara Yoshihiko 東北大学, 医学(系)研究科(研究院), 助教 (30223499)
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| Project Period (FY) |
2012-04-01 – 2016-03-31
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| Keywords | 概日リズム / 遺伝子発現 / 放射線 |
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| Outline of Final Research Achievements |
Although it is reported that radiation exposure induces the phase shift of circadian rhythm, the mechanism responsible for it is not understood. In this research, we found several circadian genes in which the phase of expression was shifted in the mouse liver using microarray analysis. However, we could not find any essential genes that plays in phase shifting of expression by irradiation in the mouse liver.
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| Free Research Field |
放射線生物学
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