2014 Fiscal Year Final Research Report
Development of highly sensitive biomolecular interaction detection system utilizing affinity peptide conjugated cushion protein as the anchor domain
Project/Area Number |
24560963
|
Research Category |
Grant-in-Aid for Scientific Research (C)
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Allocation Type | Multi-year Fund |
Section | 一般 |
Research Field |
Biofunction/Bioprocess
|
Research Institution | Okayama University |
Principal Investigator |
|
Project Period (FY) |
2012-04-01 – 2015-03-31
|
Keywords | バイオ分子 / 固定化 / 相互作用 / 超好熱菌 / タンパク質 / ペプチド / 親和性 |
Outline of Final Research Achievements |
Biomolecular immobilization is one of the basic technologies for microanalysis, diagnosis and proteome analysis. We have tried to establish the highly sensitive biomolecular interaction detection system on solid substrate by utilizing techniques of precise control of biomolecular immobilization. As the results, high interaction detection sensitivity was achieved through the combination of selected cushion protein and solid surface affinity peptide for immobilization of target biomolecule.
|
Free Research Field |
工学
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