Studies on the role of ATP receptor in taste transduction

2014 Fiscal Year Final Research Report

• Project/Area Number: 24580181
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Food science
• Research Institution: Kyoto University
• Principal Investigator: HAYASHI Yukako 京都大学, (連合)農学研究科(研究院), 准教授 (60212156)
• Project Period (FY): 2012-04-01 – 2015-03-31
• Keywords: 味覚 / 受容機構 / 味細胞 / マウス / 細胞タイプ / 味情報伝達

Outline of Final Research Achievements

Type III taste cells play to receive sour taste and also to receive taste information from type II taste cells through ATP. It had been a great mystery whether a type III taste cell acts both roles or two kinds of type III taste cells share each role separately. Our previous paper suggested that there were the two separate subpopulations of type III taste cells. Here, we focus on sour and ATP receptors . We tried to reveal sour and ATP receptor distributions in taste buds. We also attempted revealing whether ATP-responding cells have a sour receptor or not.
This studiy revealed that there are the two separate subpopulations of type III taste cells (sour-responsive cell and ATP-responsive cell to receive intercellular messenger(ATP) from type II taste cells to type III taste cells).

Free Research Field

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