Elucidation of genetic factors involving mycotoxin producibility in the fungus parasitic on rice

2014 Fiscal Year Final Research Report

• Project/Area Number: 24580474
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Boundary agriculture
• Research Institution: Gifu University
• Principal Investigator: SUGA Haruhisa 岐阜大学, 生命科学総合研究支援センター, 准教授 (20283319)
• Project Period (FY): 2012-04-01 – 2015-03-31
• Keywords: 菌類 / 遺伝子 / マイコトキシン / イネばか苗病菌 / Fusarium

Outline of Final Research Achievements

Fusarium fujikuroi is the fugal pathogen of the rice bakanae disease. Fumonisin is a mycotoxin that causes swine pulmonary edema and equine leukoencephalomalacia. Fumonisin producing population and non-producing population are present in F. fujikuroi. The causative mutations are found to be dispersed in the fumonisin biosynthetic gene cluster in a fumonisin non-producing isolate. One of the mutations is a g.2551G>T(p.G678*) substitution in FUM21 gene coding transcription factor for other fumonisin biosynthetic genes. The coding protein presumed to be disfunctioned by the missing of 11 amino acids at C-terminal derived from the substitution.

Free Research Field

菌学