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2015 Fiscal Year Final Research Report

Nano vectors with biosurfactant MEL-A

Research Project

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Project/Area Number 24590060
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Physical pharmacy
Research InstitutionAichi Gakuin University

Principal Investigator

NAKANISHI MAMORU  愛知学院大学, 薬学部, 教授 (90090472)

Co-Investigator(Kenkyū-buntansha) YAMAMOTO Hiromitsu  愛知学院大学, 薬学部, 教授 (30275094)
INHO Yoshikazu  愛知学院大学, 薬学部, 講師 (90434547)
Project Period (FY) 2012-04-01 – 2016-03-31
Keywordsnano vectors / liposome / biosurfactant / gene transfection / medical treatment / membrane fusion
Outline of Final Research Achievements

The liposomes made by biosurfactant(MEL-A) dramatically increased the efficiency in transfection of plasmid DNAs and foreign DNAs. The efficiency by nano vector is derived from the unique pathway similar to that by certain RNA virus vectors. From the safety and low toxicity the nano vector would appear to be a new operating technique with great potential in gene transfection and drug delivery in medical treatment.

Free Research Field

生物物理学

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Published: 2017-05-10  

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