2014 Fiscal Year Final Research Report
Analysis of physiological roles of membrane trafficking in neural function
| Project/Area Number |
24590341
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
General medical chemistry
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| Research Institution | Gunma University |
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Principal Investigator |
HARA Taichi 群馬大学, 生体調節研究所, 准教授 (00392374)
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| Project Period (FY) |
2012-04-01 – 2015-03-31
|
| Keywords | Rab35 / 神経細胞 / 初期発生 / 低分子量Gタンパク質 |
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| Outline of Final Research Achievements |
Small GTPase Rab35 has been suggested to be involved in intracellular membrane trafficking and neural function, although its physiological roles in mammal remained to be elucidated. In this study, we generated Rab35 deficient mice and analyzed the phenotype. We found that Rab35 deficient mice were embryonic lethal, indicating that Rab35 has an essential role in mouse early development.
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| Free Research Field |
細胞生物学
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