2014 Fiscal Year Final Research Report
The mechanism of myocardial injury from heat exposure
| Project/Area Number |
24590853
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Legal medicine
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| Research Institution | Mie University |
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Principal Investigator |
NATA Masayuki 三重大学, 医学(系)研究科(研究院), 教授 (70241627)
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| Research Collaborator |
NAKAGAWA Yasuhisa
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| Project Period (FY) |
2012-04-01 – 2015-03-31
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| Keywords | 熱中症 / 心疾患 / 心筋梗塞 / 心筋傷害 / 低酸素 / 虚血 |
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| Outline of Final Research Achievements |
Cardiac deisease is the one of the risk factor of onset of heat stroke. However, its detailed mechanisms have yet to be revealed. Therefore, We exposed heat to myocardial infarction rats, and investigated the relationship between cardiac disease and heat exposure.
In this investigation, it revealed immediately direct injury to myocardium from heat exposure. And also, it revealed possibilities that after heat exposure, heart strain from myocardial injury and myocardial ischemia are continued. In the case of cardiac disease, it is sensitive to heat exposure, and associated with a great risk of onset and exacerbation of heat stroke.
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| Free Research Field |
法医学
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