2014 Fiscal Year Final Research Report
Renin-angiotensin system and non-infectious pulmonary complication after stem cell transplantation
| Project/Area Number |
24591431
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Hematology
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| Research Institution | Tokai University |
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Principal Investigator |
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| Project Period (FY) |
2012-04-01 – 2015-03-31
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| Keywords | 造血幹細胞移植 / 移植後肺合併症 / レニン・アンジオテンシン系 / マウス肺合併症モデル |
|---|
| Outline of Final Research Achievements |
Angiotensin 1 receptor antagonist may be a candidate drug for prevent developing non-infectious pulmonary complication after hematopoietic stem cell transplantation. However, in mice transplantation model, we could not see survival benefit by AT1 receptor antagonist. But AT1 receptor antagonist reduces the incident of mice pulmonary fibrosis in the model.
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| Free Research Field |
血液内科学
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