2014 Fiscal Year Final Research Report
MRI-CFD combined analysis of brain aneurysm for initiation and growth factor of aneurysm
| Project/Area Number |
24591760
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Radiation science
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| Research Institution | Osaka University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
FUJINAKA Toshiyuki 大阪大学, 大学院医学研究科, 助教 (00359845)
WADA Shigeo (70240546)
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| Project Period (FY) |
2012-04-01 – 2015-03-31
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| Keywords | 脳動脈瘤 / 磁気共鳴画像 / 流体解析 / CFD |
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| Outline of Final Research Achievements |
We developed the new CFD analysis method using the 4D-PC-MRA flow data. Our CFD results were compared to the flow data by 4D-PC-MRA. Five unruptured cerebral aneurysms were included in this study. 3D-computational meshes were created from 3D-DSA images and CFD simulations were performed for two conditions: I= patient-specific inflow measured by 3D-PC MRA, II= patient-specific inflow and outflow measured by 3D-PC MRA. Difference in flow vector between CFD and PC-MRA was calculated at parent artery, aneurysm and distal arteries. The flow features such as vector map were similar between CFD and 4D-PC-MRA. There are no significant difference between condition I and II, but aneurysm showed statistically large flow difference compared to parent artery and distal arteries. Further study is needed to combine whole flow data of 4D-PC-MRA for CFD simulations.
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| Free Research Field |
放射線医学
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