Establishment of clinical analysis method for higher brain dysfunctions using ASL-MRI

2014 Fiscal Year Final Research Report

• Project/Area Number: 24591774
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Radiation science
• Research Institution: Research Institute, International Medical Center of Japan (2014); Saga University (2012-2013)
• Principal Investigator: NOGUCHI Tomoyuki 独立行政法人国立国際医療研究センター, その他部局等, その他 (40380448)
• Co-Investigator(Kenkyū-buntansha): 浅見 豊子 佐賀大学, 医学部, 准教授 (20222599) ; 入江 裕之 佐賀大学, 医学部, 教授 (50284493) ; 西原 正志 佐賀大学, 医学部, 助教 (50516557)
• Project Period (FY): 2012-04-01 – 2015-03-31
• Keywords: ASL / MRI / 脳機能画像 / 高次脳機能障害 / もやもや病 / 髄膜脳炎 / 脳出血 / 脳血流

Outline of Final Research Achievements

Higher brain dysfunctions such as decreased cognitive function, aphasia or memory impairment cause daily life disability or executive function impairment, which leads difficulty to have work opportunities or return to uneventful life because of excessive burden. This fact has drawn considerable attention as one of social issues. PET or SPECT as conventional brain function nuclear medicine examinations cannot be frequently performed in all patients because of expensive examinations costs and limited spread of equipments. ASL-MRI is one of MRI imaging methods measuring cerebral blood flow non-invasively. We explored the utility of ASL-MRI as an alternative imaging methods for evaluating higher brain dysfunctions.

Free Research Field

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