Molecular imaging of Kawasaki vasculitis

2014 Fiscal Year Final Research Report

• Project/Area Number: 24591798
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Radiation science
• Research Institution: Kurume University
• Principal Investigator: SUDA KENJI 久留米大学, 医学部, 准教授 (10399173)
• Co-Investigator(Kenkyū-buntansha): TAHARA Nobuhiro 久留米大学, 医学部, 准教授 (10320186) ; KUDO Yoshiyuki 久留米大学, 医学部, 助教 (10368920) ; YOSHIMOTO Hironaga 久留米大学, 医学部, 助教 (10624463) ; ISHIBASHI Masatoshi 久留米大学, 医学部, 教授 (20168256) ; IEMURA Motofumi 久留米大学, 医学部, 助教 (30399175)
• Project Period (FY): 2012-04-01 – 2015-03-31
• Keywords: ポジトロンエミッショントモグラフィー / 川崎病 / 冠動脈瘤

Outline of Final Research Achievements

More than 14,000 Japanese children are suffered from Kawasaki diesase, a most prevalent vasculitis in developed countries and about 1% of them left with coronary aneurysms as sequelae. Though coronary aneurysms show remodeling with intimal thickenning, leading to ischemic heart disease, the mechanisms of this remodeing is unknown. In this study with positron emission tomography using 18 fluorodeoxyglucose, we have demonstrated that indeed local inflammation of coronary artery aneurysms persist long after Kawasaki disease.

Free Research Field

小児循環器