Intra-operative diagnosis of cerebral infarction by MEP (motor evoked potential)

2015 Fiscal Year Final Research Report

• Project/Area Number: 24592070
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Thoracic surgery
• Research Institution: University of the Ryukyus
• Principal Investigator: KUNIYOSHI Yukio 琉球大学, 医学(系)研究科(研究院), 教授 (50153317)
• Co-Investigator(Kenkyū-buntansha): KISE Yuya 琉球大学, 医学部附属病院, 助教 (00468076) ; NAGANO Takaaki 琉球大学, 医学部附属病院, 助教 (50363669) ; YAMASHIRO Satoshi 琉球大学, 医学(系)研究科(研究院), 准教授 (80315465) ; INAFUKU Hitoshi 琉球大学, 医学部附属病院, 講師 (30404578)
• Project Period (FY): 2012-04-01 – 2016-03-31
• Keywords: MEP / Hypothermia / cerebral infarction

Outline of Final Research Achievements

The experimental study was carried out for rapid detection of newly developed cerebral infarction by MEP (motor evoked potential). It has been generally accepted that the early diagnosis and treatment of cerebral infarction makes better prognosis.
To establish rapid diagnostic method for cerebral infarction during aortic arch surgery, MEP was evaluated for methodology of the purpose above. Result-1) MEP is definitely detected by setting cathode at mastoid process, and anode at submandibular soft tissue at the temperature range from 38 degrees C. to 20 degrees C.. Results-2) The latent time of MEP was measured 2.8 msec. on average, and was constant among whole range of body temperature. The experimental protocol above could be useful for studying the conduction system of cerebral-spinal nervous system, and also establishment of rapid diagnosis of intraoperative cerebral infarction in hypothermia.

Free Research Field

心臓血管外科