2014 Fiscal Year Final Research Report
Functional analysis for the cytokines produced by ASC and ASC-induced restoration of erectile function.
| Project/Area Number |
24592423
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Urology
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| Research Institution | The University of Tokyo |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
SUZUKI Etsu 聖マリアンナ医科大学, 医学系研究科, 講師 (40313134)
TAKAHASHI Masao 東京大学医学部附属病院, 循環器内科, 助教 (00447418)
NOMIYA Akira 東京大学医学部附属病院, 泌尿器外科学, 助教 (30372379)
HIRATA Yasunobu 東京大学医学部附属病院, 循環器内科, 准教授 (70167609)
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| Project Period (FY) |
2012-04-01 – 2015-03-31
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| Keywords | 脂肪幹細胞 / 勃起不全治療 |
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| Outline of Final Research Achievements |
The aim of this study is to explore a better treatment for ED, we examined whether combination of AM and angiopoietin-1 (Ang-1) was more effective to treat ED than treatment with AM alone or Ang-1 alone. We also compared the effect of the combination therapy with that of treatment with vascular endothelial growth factor-A (VEGF-A).
Combination therapy with AM and Ang-1 potently restored erectile function and normal morphology of the cavernous body compared with VEGF-A administration. This combination therapy will be useful to treat ED patients with a severely damaged cavernous body.
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| Free Research Field |
泌尿器外科学
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