2015 Fiscal Year Final Research Report
Development of new procedure of diaphragmatic repair using tissue engineering approach
| Project/Area Number |
24592691
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Pediatric surgery
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| Research Institution | University of Tsukuba |
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Principal Investigator |
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| Co-Investigator(Renkei-kenkyūsha) |
MASUMOTO Kouji 筑波大学, 医学医療系, 教授 (20343329)
CHEN Guoping 独立行政法人物質, 材料機構・生体材料工学研究所, 主幹研究員 (50357505)
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| Project Period (FY) |
2012-04-01 – 2016-03-31
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| Keywords | 先天性横隔膜ヘルニア / PLGA / Hybrid Scaffold / 骨格筋 |
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| Outline of Final Research Achievements |
In order to improve the Quality of life and prevention of the thorax deformation after the introduction of the artificial membrane in congenital diaphragmatic hernia(CDH) treatment, CDH rat model had been development.
When the folding sheet was sewing, an omentum leaving a vascular system with its pedicle was interposed between the sheets. We have developed a new CDH repair procedure in order to examine whether it is possible to muscle regeneration by the omentum that is fed by the blood vessels into "new diaphragm".
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| Free Research Field |
小児外科
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