Development of a high-performance nanobiological interface control method for bioactive surface modification of hydroxyapatite with UV/ozone

2014 Fiscal Year Final Research Report

• Project/Area Number: 24592915
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Prosthetic dentistry
• Research Institution: Hiroshima University
• Principal Investigator: ABE Yasuhiko 広島大学, 医歯薬保健学研究院, 准教授 (00253097)
• Co-Investigator(Kenkyū-buntansha): HIRATA Isao 広島大学, 大学院医歯薬保健学研究院, 助教 (40346507)
• Project Period (FY): 2012-04-01 – 2015-03-31
• Keywords: 生体材料 / セラミックス / ナノバイオ / 表面・界面物性 / アパタイト / 紫外線

Outline of Final Research Achievements

The purpose of this study was to evaluate the effect of UV/ozone treatment on hydroxyapatite and establish the high-performance nanobiological interface control method for bioactive surface modification of hydroxyapatite. The 5-minute UV/ozone treatment could validate for the surface decontamination, the improvement and 7-day maintenance of wettability, and the acceleration of the adhesion and proliferation of MC3T3-E1 cells. Therefore, the UV/ozone treatment for the interface control between hydroxyapatite and bone was developed.

Free Research Field

歯科補綴学，生体材料学