2014 Fiscal Year Final Research Report
Inorganic polyphosphate adsorbed onto hydroxyapatite for guided bone regeneration of implantitis
| Project/Area Number |
24592918
|
|---|
| Research Category |
Grant-in-Aid for Scientific Research (C)
|
| Allocation Type | Multi-year Fund |
|---|
| Section | 一般 |
|---|
| Research Field |
Prosthetic dentistry
|
|---|
| Research Institution | Hiroshima University |
|---|
Principal Investigator |
DOI KAZUYA 広島大学, 大学院医歯薬保健学研究院, 助教 (80444686)
|
|---|
| Co-Investigator(Kenkyū-buntansha) |
MORITA Koji 広島大学, 病院, 助教 (30555149)
KUREMOTO Koichi 広島大学, 大学院医歯薬保健学研究院, 助教 (90319583)
|
|---|
| Project Period (FY) |
2012-04-01 – 2015-03-31
|
| Keywords | インプラント周囲炎 / ポリリン酸 / 人工骨 |
|---|
| Outline of Final Research Achievements |
The development of a bone regeneration therapy using a long chain length inorganc polyphosphates for implantitis. Long chain;300 polyphosphate was improved the contaminated titanium plate. Also,in inflammatory macrophage test by LPS addition, polyphosphoric inhibited nitric oxide expression.In animal study, inorganic polyphosphate adsorbed onto hydroxyapatite promote bone regeneration on fenestrated bonedefect around implant.
|
| Free Research Field |
歯科補綴
|
