Inorganic polyphosphate adsorbed onto hydroxyapatite for guided bone regeneration of implantitis
| Project/Area Number |
24592918
|
|---|
| Research Category |
Grant-in-Aid for Scientific Research (C)
|
| Allocation Type | Multi-year Fund |
|---|
| Section | 一般 |
|---|
| Research Field |
Prosthetic dentistry
|
|---|
| Research Institution | Hiroshima University |
|---|
Principal Investigator |
DOI KAZUYA 広島大学, 大学院医歯薬保健学研究院, 助教 (80444686)
|
|---|
| Co-Investigator(Kenkyū-buntansha) |
MORITA Koji 広島大学, 病院, 助教 (30555149)
KUREMOTO Koichi 広島大学, 大学院医歯薬保健学研究院, 助教 (90319583)
|
|---|
| Project Period (FY) |
2012-04-01 – 2015-03-31
|
| Project Status |
Completed (Fiscal Year 2014)
|
| Budget Amount *help |
¥5,200,000 (Direct Cost: ¥4,000,000、Indirect Cost: ¥1,200,000)
Fiscal Year 2014: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2013: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
Fiscal Year 2012: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
|
|---|
| Keywords | インプラント周囲炎 / ポリリン酸 / 人工骨 |
|---|
| Outline of Final Research Achievements |
The development of a bone regeneration therapy using a long chain length inorganc polyphosphates for implantitis. Long chain;300 polyphosphate was improved the contaminated titanium plate. Also,in inflammatory macrophage test by LPS addition, polyphosphoric inhibited nitric oxide expression.In animal study, inorganic polyphosphate adsorbed onto hydroxyapatite promote bone regeneration on fenestrated bonedefect around implant.
|
Report
(4 results)
Research Products
(8 results)
