2014 Fiscal Year Final Research Report
Cell sheets were prepared and layered to produce a hybrid cell sheet
| Project/Area Number |
24593061
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Surgical dentistry
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| Research Institution | Tokyo Dental College |
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Principal Investigator |
ABE Shinichi 東京歯科大学, 歯学部, 教授 (40256300)
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| Project Period (FY) |
2012-04-01 – 2015-03-31
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| Keywords | 筋シート / 細胞シート / デスミン / ケラチン |
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| Outline of Final Research Achievements |
In the present study, cell sheets were prepared using cells extracted from the oral mucosal epithelium, subepithelial tissue of the oral mucosa, and muscle tissue, and layered to produce a hybrid cell sheet. In the layered sheet, the mucosal epithelium, connective tissue layer, and muscle layer and their specific proteins increased over time with stratification. Specifically, the same structural proteins as those in vivo were expressed in the sheet.
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| Free Research Field |
口腔解剖
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