Development of regenerative medicine of tooth root resorption using phosphorylated pullulan

2014 Fiscal Year Final Research Report

• Project/Area Number: 24593074
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Orthodontic/Pediatric dentistry
• Research Institution: Tohoku University
• Principal Investigator: IKEDA Etsuko 東北大学, 歯学研究科(研究院), 大学院非常勤講師 (20509012)
• Co-Investigator(Kenkyū-buntansha): YAMAMOTO Teruko 東北大学, 歯学研究科, 教授 (00127250) ; TAKESHITA Nobuo 東北大学, 歯学研究科, 助教 (50431515)
• Project Period (FY): 2012-04-01 – 2015-03-31
• Keywords: 再生医療 / リン酸化プルラン / 歯根

Outline of Final Research Achievements

Tooth root resorption is one of side effects of orthodontic treatment. In the present study, we have performed the basic research directing development of regenerative medicine of the tooth root resorption using a novel biomaterial, phosphorylated pullulan. As a result, we achieved elucidation of the effects of phosphorylated pullulan on cell activities, acquirement of cell seeds, and establishment of cell manipulation technique. These findings will contribute to establishment of the regenerative medicine of the tooth root resorption in the future.

Free Research Field

医歯薬学