Accumulation of repeated irradiation on children's health

2014 Fiscal Year Final Research Report

• Project/Area Number: 24600029
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: 子ども学(子ども環境学)
• Research Institution: National Institute of Radiological Sciences
• Principal Investigator: SHIMADA Yoshiya 独立行政法人放射線医学総合研究所, 放射線防護研究センター, 副センター長 (10201550)
• Co-Investigator(Kenkyū-buntansha): NISHIMURA Mayumi 国立研究開発法人放射線医学総合研究所, 放射線防護研究センター, 主任研究員 (70218204)
• Project Period (FY): 2012-04-01 – 2015-03-31
• Keywords: 放射線 / 発がん / 子ども

Outline of Final Research Achievements

Children are known to be susceptible to radiation-associated health effects. Recent public concern is focued on the repeated CT examination, especially to children. In this study, the effect of repeated exposure was compared to acute exposure in both infant (1 week of age) and adult (7 week of age) mice. It turned out that the effect of radiation on lifespan shortening and T-cell lymphoma development in infant mice was dependent on the interval of each exposure: the daily exposure was more effective than weekly exposure and acute exposure. On the other hand, the effect on adult mice showed no dependence on exposure regimen.
The local survey for childhood CT exposure was conducted. As a result, CTDI and DLP were almost comparble to international DRL. The numerical values of various CT examinations after nationa-wide survey were adopted as Japan national DRL.

Free Research Field

放射線発がん