2012 Fiscal Year Final Research Report
The effect of reciprocal fixation to keep muscle strength secondary to joint immobilization
| Project/Area Number |
24650327
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Rehabilitation science/Welfare engineering
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| Research Institution | Prefectural University of Hiroshima |
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Principal Investigator |
OKI Sadaaki 県立広島大学, 保健福祉学部, 教授 (10194466)
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| Project Period (FY) |
2012
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| Keywords | リハビリテーション医学 / 廃用性筋萎縮 |
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| Research Abstract |
To investigate the effect of reciprocal fixation to keep muscle strength secondary to joint immobilization, an experimental study was carried out. Twenty-four female Wistar rats were used in this study. The rats were divided into four groups (extension fixation group, flexion fixation group, reciprocal fixation group, and control group), each group containing 6 rats. For the extension fixation group, unilateral ankle cast fixations were carried out in extension position. For the flexion fixation group, unilateral ankle cast fixations were carried out in full flexion position. For the reciprocal fixation group, unilateral ankle cast fixations were carried out in full extension position (8 hours a day) and full flexion position (16 hours a day) reciprocally. For the control group, joint fixations were not carried out. After 4 days, isometric twitch tension, maximum tetanic tension, relative weight ratio, and histological change of soleus and tibialis anterior muscles were examined. Muscle atrophy was prevented in the reciprocal fixation group. The maximum tetanic tension of tibialis anterior muscles in the reciprocal fixation group was not enough to the control group. Further maneuver in addition to the reciprocal fixation is needed to keep muscle strength.
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