2013 Fiscal Year Final Research Report
The initial diagnosis for lung cancer using isotope ratio
| Project/Area Number |
24650635
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Single-year Grants |
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| Research Field |
Tumor diagnosis
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| Research Institution | Akita Prefectural University |
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Principal Investigator |
KAWASHIMA Hiroto 秋田県立大学, システム科学技術学部, 助教 (60381331)
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| Project Period (FY) |
2012-04-01 – 2014-03-31
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| Keywords | 肺がん / 初期診断 / 安定同位体比 / 分析化学 |
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| Research Abstract |
For the development of the inspection method for lung cancer, we conducted various tests. As the results, the developed method can be measured lot of VOCs for high accuracy, and reduced a patient burden by small exhalation. As the exhalation test, there is almost no difference exhalation by different food and no long time by prohibited food and drinks before exhalation test. The exhalation for smokers included benzene than non-smoker. The benzene of exhalation was decreasing after smoking 6 hours. And, the exhalation for smoking menthol cigarettes included high level benzene and toluene. Using thermal desorption system, carbon isotope for many VOCs can be measured for high precision and accuracy.
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