2013 Fiscal Year Final Research Report
Dynamics of artificial self-supported lipid membranes
| Project/Area Number |
24655056
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Single-year Grants |
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| Research Field |
Analytical chemistry
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| Research Institution | Chiba University |
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Principal Investigator |
FUJINAMI Masanori 千葉大学, 工学(系)研究科(研究院), 教授 (50311436)
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| Co-Investigator(Renkei-kenkyūsha) |
TOYOTA Taro 東京大学, 大学院総合文化研究科, 准教授 (80422377)
NOMOTO Tomonori 千葉大学, 大学院工学研究科, 助教 (00510520)
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| Project Period (FY) |
2012-04-01 – 2014-03-31
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| Keywords | 膜張力 / 脂質二分子膜 / レーザー誘起界面変形分光法 / 光学顕微鏡 / コレステロール / 脂質分子 |
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| Research Abstract |
In this study, we have developed a methodology of detecting interfacial tension and related properties of a planar artificial self-supported lipid membrane, or black lipid membrane (BLM) for studying fluctuations and mechanical/chemical properties of biomembranes. Laser-induced surface deformation spectroscopy was applied by optimizing the refractive indices of two water phases. As a result, measurement of fluctuation and interfacial tension of BLM has been succeeded and their dependence on its compositions and molecular was discussed.
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