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2013 Fiscal Year Final Research Report

Development of in vitro embryotoxic test for nanomaterials

Research Project

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Project/Area Number 24659075
Research Category

Grant-in-Aid for Challenging Exploratory Research

Allocation TypeSingle-year Grants
Research Field Medical pharmacy
Research InstitutionOsaka University

Principal Investigator

YOSHIOKA Yasuo  大阪大学, 薬学研究科(研究院), 准教授 (00392308)

Project Period (FY) 2012-04-01 – 2014-03-31
Keywordsナノマテリアル / 生殖発生毒性 / 安全性
Research Abstract

Recently, research into potential safety of nanomatelials is increasing. However, few studies are examined the embryotoxicity of nanomatelials. Therefore, we had investigated the embryotoxicity of nanomatelials, and revealed that some nanomatelials might have a potential to cause pregnancy complications. To assess more detail embryotoxicity of nanomatelials, we tried to accumulate the basic information for the development of embryotoxicity method of nanomatelials in vitro.

  • Research Products

    (3 results)

All 2012

All Presentation (3 results)

  • [Presentation] Postnatal effects of prenatal exposure to amorphous nanosilica particles on neonatal cognitive functions2012

    • Author(s)
      Morishita Y., Yoshioka Y., Takao K., Ago Y., Satoh H., Nojiri N., Takuma K., Tsunoda S., Nabeshi H., Yoshikawa T., Matsuda T., Miyakawa T., Tsutsumi Y.
    • Organizer
      SETAC Asia/Pacific 2012
    • Place of Presentation
      Kumamoto, Japan
    • Year and Date
      20120924-27
  • [Presentation] In vitro evaluation of the embryotoxic potency of amorphous nanosilica2012

    • Author(s)
      Ogura T., Yoshioka Y., Yamashita K., Taira M., Aoyama M., Tsunoda S., Kawabata K., Mizuguchi H., Nabeshi H., Yoshikawa T., Tsutsumi Y.
    • Organizer
      The 6^<th> International Conference on Nanotoxicology (Nanotoxicology 2012)
    • Place of Presentation
      Beijing, China
    • Year and Date
      20120904-07
  • [Presentation] サブナノ素材の妊娠期曝露による胎仔影響の基礎検討2012

    • Author(s)
      佐藤宏祐, 吉岡靖雄, 森下裕貴, 野尻奈央, 角田慎一, 鍋師裕美, 吉川友章, 堤康央
    • Organizer
      第39回日本毒性学会学術年会
    • Place of Presentation
      仙台, 宮城
    • Year and Date
      20120700

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Published: 2015-06-25  

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