How do Kampo formulations work?

2014 Fiscal Year Final Research Report

• Project/Area Number: 24659348
• Research Category: Grant-in-Aid for Challenging Exploratory Research
• Allocation Type: Multi-year Fund
• Research Field: General internal medicine (including Psychosomatic medicine)
• Research Institution: University of Toyama
• Principal Investigator: SAIKI Ikuo 富山大学, 和漢医薬学総合研究所, 教授 (80133776)
• Co-Investigator(Kenkyū-buntansha): YOKOYAMA Satoru 富山大学, 和漢医薬学総合研究所, 助教 (90613498)
• Project Period (FY): 2012-04-01 – 2015-03-31
• Keywords: 漢方薬 / 構成生薬 / 細胞内シグナル

Outline of Final Research Achievements

Kampo formulations comprise a number of crude natural drugs/herbs as constituents. The crude drugs/herbs have been traditionally classified by their traditional classifications or efficacies in Kampo medicines; however, it has been difficult to establish the scientific link between experimental evidence and traditional classifications in Kampo medicine.
Consideringour results supported by the grant, the traditional categories of crude drugs/herbs in Kampo medicine may be positively associated with the effects on intracellular signaling using reporter assay unless there are significant differences in their botanical origin and active constituents. Alternatively, our results imply that the crude drugs/herbs belonging to the same category in Kampo medicine share a common effect on intracellular signaling activity in vitro.

Free Research Field

腫瘍生物学