2013 Fiscal Year Final Research Report
Development of endoscopic treatment system using laser
| Project/Area Number |
24659366
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Single-year Grants |
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| Research Field |
Gastroenterology
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| Research Institution | Kobe University |
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Principal Investigator |
AZUMA Takeshi 神戸大学, 医学(系)研究科(研究院), 教授 (60221040)
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| Co-Investigator(Kenkyū-buntansha) |
TOYONAGA Takashi 神戸大学, 医学部附属病院, 准教授 (40464268)
MORITA Yoshinori 神戸大学, 医学部附属病院, 講師 (60420460)
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| Project Period (FY) |
2012-04-01 – 2014-03-31
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| Keywords | 消化器内視鏡 / レーザー / 内視鏡治療 |
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| Research Abstract |
We developed CO2 laser system with flexible thin hollow optical fibers transmitting mid-infrared light. The energy of the CO2 laser was absorbed by the water and did not reach the muscularis propria of GI tract. In the ex vivo and in vivo study using pigs, en bloc resections were achieved without perforation and muscular damage. Endoscopic submucosal dissection using a CO2 laser with a submucosally injected laser absorbent might be a feasible method for the treatment of early GI tract cancer.
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