2014 Fiscal Year Final Research Report
Establishing the basic study for unmyelinated and myelinated central nervous system
| Project/Area Number |
24659436
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Neurology
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| Research Institution | The Institute of Physical and Chemical Research |
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Principal Investigator |
NUKINA Nobuyuki 独立行政法人理化学研究所, 脳科学総合研究センター, 客員主管研究員 (10134595)
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| Project Period (FY) |
2012-04-01 – 2015-03-31
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| Keywords | 無髄線維 / 線条体投射線維 / sodium channel / beta4 subunit / Nav1.2 |
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| Outline of Final Research Achievements |
The role of unmyelinated fiber in central nervous system is not well elucidated. Even which nervous system is unmylinated is well unknown. We recently found the striatal projection fibers are unmylinated suggested by the distribution pattern of sodium channel beta4 subunit. In this study we further confirm this fact and identified several features of those unmyelinated fibers(Miyazaki et al Nat Commun2014)
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| Free Research Field |
病態脳科学
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