2013 Fiscal Year Final Research Report
Explorative study for development of a novel therapy for steroid-induced muscle atrophy
| Project/Area Number |
24659471
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Single-year Grants |
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| Research Field |
膠原病・アレルギー・感染症内科学
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| Research Institution | The University of Tokyo |
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Principal Investigator |
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| Project Period (FY) |
2012-04-01 – 2014-03-31
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| Keywords | 膠原病 / 内科 / 臨床 / 筋萎縮 |
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| Research Abstract |
We examined the effectiveness of branched-chain amino acids for steroid-treated rheumatic disease patients. We also developed the assays such as X-rays CT, the MRI for determination of muscle mass. I set 20 cases to aim number of cases, and 15 cases are finished at present.
From middle analysis, our intervention is suggested to give a certain effect. We are now preparing for multicenter investigation.
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Research Products
(14 results)
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[Journal Article] Quantitative analysis of skeletal muscle mass in patients with rheumatic diseases under glucocorticoid therapy - comparison among bioelectrical impedance analysis, computed tomography, and magnetic resonance imaging
Author(s)
Osamu Hosono, Noritada Yoshikawa, Noriaki Shimizu, Shigeru Kiryu, Masaaki Uehara, Hiroshi Kobayashi, Ryo Matsumiya, Akiko Kuribara, Takako Maruyama, Hirotoshi Tanaka
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Journal Title
Modern Rheumatol
Volume: (In press)
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[Presentation] グルココルチコイドによる骨格筋線維タイプ特異的な代謝の生理的調節機構2013
Author(s)
清水宣明,丸山崇子,伊藤尚基,武田伸一,栗原明子,馬艶霞,松宮遼,小林弘,吉川賢忠,細野治,田中廣壽
Organizer
第21回日本ステロイドホルモン学会学術集会
Place of Presentation
千里ライフサイエンスセンター,豊中市
Year and Date
2013-11-16
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[Presentation] グルココルチコイドレセプターの骨格筋線維タイプ特異的な役割の解析2013
Author(s)
清水宣明,吉川賢忠,丸山崇子,栗原明子,馬艶霞,松宮遼,松橋智弘,佐野元昭,福田恵一,田中廣壽
Organizer
第86回日本内分泌学会学術総会
Place of Presentation
仙台国際センター,仙台市
Year and Date
2013-04-26
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