Development of a metallic iron nanoparticle-based MRI agent

2014 Fiscal Year Final Research Report

• Project/Area Number: 24681022
• Research Category: Grant-in-Aid for Young Scientists (A)
• Allocation Type: Partial Multi-year Fund
• Research Field: Nanomaterials/Nanobioscience
• Research Institution: Kyoto University
• Principal Investigator: YAMAMOTO Shinpei 京都大学, 物質-細胞統合システム拠点, 助教 (20362395)
• Project Period (FY): 2012-04-01 – 2015-03-31
• Keywords: iron nanoparticles

Outline of Final Research Achievements

Development of a new magnetic resonance imaging agent based on metallic iron nanoparticles was conducted and following results were obtained: (a) successful synthesis of iron oxide-coated metallic iron nanoparticles having a very high saturation magnetization (Ms > 170 emu/g) and excellent stability in air (decrement of Ms during exposure to air is less than 10 % up to 1000 hrs) and (b) successful atom transfer radical graft polymerization of polyethylene glycol monomethacrylate from the nanoparticles, giving dispersion stability and a “stealth” character.

Free Research Field

magnetic nano-materials