Development of Chemoselective Carbon-Carbon Bond Formation Reactions Directed toward Synthesis of Functional Molecules

2014 Fiscal Year Final Research Report

• Project/Area Number: 24685015
• Research Category: Grant-in-Aid for Young Scientists (A)
• Allocation Type: Partial Multi-year Fund
• Research Field: Synthetic chemistry
• Research Institution: Hokkaido University
• Principal Investigator: OHMIYA Hirohisa 北海道大学, 理学(系)研究科(研究院), 准教授 (40508876)
• Project Period (FY): 2012-04-01 – 2015-03-31
• Keywords: 銅触媒 / 不斉合成 / 有機ホウ素化合物 / C-H官能基化 / アリル化

Outline of Final Research Achievements

The researcher developed unprecedented synthetic reactions based on the catalyst design focusing on a characteristic feature of copper that is relatively resistant to oxidation state change. Specifically, he developed new types of highly selective carbon-carbon bond formation reactions of organoboron compounds with copper catalyst systems. This research has been expanded to catalytic enantioselective carbon-carbon bond formation reactions. The focus of the research has shifted to catalytic C-H functionalization for stereoselective carbon-carbon bond formation reactions. The achievement has pioneered the potential of copper chemistry, and established new designing concepts of copper catalysis.

Free Research Field

有機合成化学