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2013 Fiscal Year Final Research Report

Investigation of inhibitory effects of plant extracts on toxin type food poisoning and its applications

Research Project

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Project/Area Number 24700806
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Eating habits, studies on eating habits
Research InstitutionUniversity of Shizuoka

Principal Investigator

SHIMAMURA YUKO  静岡県立大学, 食品栄養科学部, 助教 (60452025)

Project Period (FY) 2012-04-01 – 2014-03-31
Keywords黄色ブドウ球菌 / ポリフェノール / エンテロトキシンA
Research Abstract

The aims of the present study are first to investigate the binding activities of plant extracts and its components (n=136) to staphylococcal enterotoxin A (SEA), and second to examine the inhibitory effects of these extracts and components on the production and toxic activity of SEA. As a result, 26 samples inhibited the binding affinity of the anti-SEA antibody to SEA. Although highly polymerized proanthocyanidins in apple extract was bound with SEA directly, lowly polymerized proanthocyanidins inhibited the toxic activity without binding with SEA. Hydroxyl group at position 3 of galloyl group in catechin structure was responsible for binding affinity with the SEA. However methylated-catechins (methyl group at position 3 or 4 of galloyl group) showed inhibitory effect on production and toxic activity of SEA. It was suggested that these inhibitory effects were not necessarily related to the binding affinity of SEA.

  • Research Products

    (14 results)

All 2014 2013 2012 Other

All Journal Article (5 results) Presentation (8 results) Remarks (1 results)

  • [Journal Article] Identification of the phenolic compounds contributing to antibacterial activity in ethanol extracts of Brazilian red propolis2014

    • Author(s)
      Inui S, Hatano A, Yoshino M, Hosoya T, Shimamura Y, Masuda S, Ahn MR, Tazawa S, Araki Y, Kumazawa S
    • Journal Title

      Nat Prod Res

      Volume: (Epub ahead of print)

    • DOI

      10.1080/14786419.2014.898146

  • [Journal Article] Pu-erh Tea Suppresses Diet-Induced Body Fat Accumulation in C57BL/6J Mice by Down-Regulating SREBP-1c and Related Molecules2013

    • Author(s)
      Shimamura Y, Yoda M, Sakakibara H, Matsunaga K, Masuda S
    • Journal Title

      Biosci. Biotechnol. Biochem.

      Volume: 77(7) Pages: 1145-1160

    • DOI

      10.1271/bbb.130097

  • [Journal Article] Reason why food poisoning bacteria attached to shredded cabbage are not efficiently disinfected with sodium hypochlorite2013

    • Author(s)
      Nakanishi Y, Kawamura S, Tsutsuura S, Shimamura Y, Murata M
    • Journal Title

      Biosci. Biotechnol. Biochem.

      Volume: 77(6) Pages: 1160-1165

    • DOI

      10.1271/bbb.120087

  • [Journal Article] Temperature Dependence of the production of staphylococcal enterotoxin A by Staphylococcus aureus2013

    • Author(s)
      Tsutsuura S, Shimamura Y, Murata M
    • Journal Title

      Biosci. Biotechnol. Biochem.

      Volume: 77(1) Pages: 30-37

    • DOI

      10.1271/bbb.120391

  • [Journal Article] Solophenols B-d and solomonin : new prenylated polyphenols isolated from propolis collected from the solomon islands and their antibacterial activity2012

    • Author(s)
      Inui S, Hosoya T, Shimamura Y, Masuda S, Ogawa T, Kobayashi H, Shirafuji K, Moli RT, Kozone I, Shin-Ya K, and Kumazawa S
    • Journal Title

      J. Agric. Food Chem.

      Volume: 60 Pages: 11765-11770

    • DOI

      10.1021/jf303516w

  • [Presentation] 食中毒菌の毒素産生および活性に対するカテキン類の抑制効果2014

    • Author(s)
      杉山由華,島村裕子,菅敏幸,増田修一
    • Organizer
      日本農芸化学会2014年度大会
    • Place of Presentation
      東京
    • Year and Date
      20140300
  • [Presentation] Screening of tea extract and theaflavins for inhibitory effects on the biological activity and production of staphylococcal enterotoxin A2013

    • Author(s)
      Sugiyama Y, Shimamura Y, Aoki N, Nakayama T, Masuda S
    • Organizer
      Shizuoka forum on health and longevity
    • Place of Presentation
      Shizuoka
    • Year and Date
      20131101-02
  • [Presentation] 食中毒菌の毒素産生および活性を抑制する植物食品の探索2013

    • Author(s)
      青木菜摘,島村裕子,田中隆,村田容常,増田修一
    • Organizer
      日本農芸化学会2013年度大会
    • Place of Presentation
      仙台
    • Year and Date
      20130324-28
  • [Presentation] 食肉中の食中毒菌の分布と電解水による殺菌効果に関する研究2013

    • Author(s)
      平石美季,島村裕子,新家桃香,佐藤勝浩,青野博志,青野盈瓠,篠田和代、村田容常,増田修一
    • Organizer
      日本食品衛生学会第106回学術講演会
    • Place of Presentation
      沖縄
    • Year and Date
      2013-11-22
  • [Presentation] 食中毒菌の毒素産生および活性に対するリンゴ由来プロアントシアニジン画分の抑制効果2013

    • Author(s)
      杉山由華,島村裕子,柳田顕郎,増田修一
    • Organizer
      日本農芸化学会中部支部第168回例会
    • Place of Presentation
      名古屋
    • Year and Date
      2013-10-12
  • [Presentation] 黄色ブドウ球菌エンテロトキシンA産生株の溶菌に影響する環境因子の解明2013

    • Author(s)
      柴田昌治,島村裕子,増田修一
    • Organizer
      日本農芸化学会中部支部第168回例会
    • Place of Presentation
      名古屋
    • Year and Date
      2013-10-12
  • [Presentation] Screening of plant extracts for inhibitory effects on the production and biological activity of bacterial toxins2012

    • Author(s)
      Natsumi Aoki, Yuko Shimamura, Takashi Tanaka, Masatsune Murata, and Shuichi Masuda
    • Organizer
      The 1st international conference on pharma and food
    • Place of Presentation
      Shizuoka
    • Year and Date
      20121115-16
  • [Presentation] Solophenols and solomonin; new prenylated polyphenols isolated from propolis collected from the Solomon Islands and their antibacterial activity2012

    • Author(s)
      Saori Inui, Takahiro Hosoya, Yuko Shimamura, Shuichi Masuda, Kenichi Shirafuji, Reuben Toli Moli, Shigenori Kumazawa
    • Organizer
      The 1st international conference on pharma and food
    • Place of Presentation
      Shizuoka
    • Year and Date
      20121115-16
  • [Remarks]

    • URL

      http://sfns.u-shizuoka-ken.ac.jp/foodhygn/index.html

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Published: 2015-06-25  

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