2014 Fiscal Year Final Research Report
Development of sarcomere-like microactuators driven by motor proteins
| Project/Area Number |
24760203
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Intelligent mechanics/Mechanical systems
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| Research Institution | Gifu University |
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Principal Investigator |
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| Project Period (FY) |
2012-04-01 – 2015-03-31
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| Keywords | モーター蛋白質 / 細胞骨格 / 微細加工 / マイクロアクチュエータ / シミュレーション |
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| Outline of Final Research Achievements |
Motor proteins, such as kinesin and myosin, are biological molecular machines working in cells, and have been integrated into MEMS and lab-on-a-chips as their driving forces. Here, we aimed at developing a microactuator with motor proteins and cytoskeletal filaments anchored onto microfabricated scaffolds. To this end, we fabricated microscopic cylindrical particles serving as the scaffolds, and bound them with motor proteins and cytoskeletons. In addition, we developed a computer simulation which aids the development of the microactuator.
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| Free Research Field |
応用物理
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