2013 Fiscal Year Final Research Report
Functional analysis of relaxins in teleosts
| Project/Area Number |
24770057
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Morphology/Structure
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| Research Institution | The University of Tokyo |
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Principal Investigator |
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| Project Period (FY) |
2012-04-01 – 2014-03-31
|
| Keywords | リラキシン / ニューロペプチド / 浸透圧調節 / 真骨魚類 |
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| Research Abstract |
The results of the changes in relaxin-related peptide gene expression in the brain of the three-spined stickleback with different salinity environment showed that most of the relaxin-related peptides responded to changes in environmental salinity. A relaxin gene expression that is classified as rln3b in the brain of three-spined stickleback in particular has significantly increased with an increase of the environmental salinity. Further, the expression patterns of receptors of relaxin-related genes differ between seawater and freshwater type stickleback. These results support the possibility of osmoregulatory functions of relaxin-related peptides in teleost fish.
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