2013 Fiscal Year Final Research Report

Development of siRNA based anti Nidovirus drug against mosquito

Research Project

Project/Area Number	24790134
Research Category	Grant-in-Aid for Young Scientists (B)
Allocation Type	Multi-year Fund
Research Field	Environmental pharmacy
Research Institution	Fukuoka University
Principal Investigator	SATHO Tomomitsu 福岡大学, 薬学部, 助教 (90369025)
Project Period (FY)	2012-04-01 – 2014-03-31
Keywords	コガタアカイエカ / ニドウイルス
Research Abstract	Dak Nong Virsu (DKNV) was isolated from Culex tritaeniorhynchus collected in Vietnam. Electron microscopic analysis showed that DKNV is enveloped, spherical virus with an diameter of 80nm. The complete genome sequence of DKNV was 20256bp and its genome appeared to contain at least seven ORFs. DKNV RdRp sequence was most similar to that of the members of the species Alphamesonivirus1 (Cavally virus and Nam Dinh virus) in the genus Alphamesonivirus of the family Mesoniviridase.

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