2014 Fiscal Year Final Research Report
Establishment of preliminary environmental risk assessment for chemicals with a biomimetic receptor and high-performance liquid chromatography
| Project/Area Number |
24790135
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Environmental pharmacy
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| Research Institution | National Institute for Agro-Environmental Sciences |
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Principal Investigator |
WATANABE Eiki 独立行政法人農業環境技術研究所, その他部局等, 主任研究員 (30354129)
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| Project Period (FY) |
2012-04-01 – 2015-03-31
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| Keywords | 環境化学 / 分析化学 / 分子認識素子 |
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| Outline of Final Research Achievements |
A preliminary method of forecasting the estrogenic revitalization that is used to evaluate the influence of chemicals on human health or ecosystem was established by combining well-established high-performance liquid chromatography with a biomimetic receptor molecule, "molecularly imprinted polymer" that can be artificially created. The estimated values of the relative revitalization obtained from the proposed method and the well-established bioassay method used as a reference method in this study showed a roughly similar tendency. That is, it was concluded that the proposed method was appropriate as a technique for preliminarily forecasting the estrogenic revitalization.
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| Free Research Field |
分析化学
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