A study of the mechanisms involved in the atmospheric pressure change detection

2014 Fiscal Year Final Research Report

• Project/Area Number: 24790239
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Multi-year Fund
• Research Field: Environmental physiology (including Physical medicine and Nutritional physiology)
• Research Institution: Keio University
• Principal Investigator: MEGUMI Funakubo 慶應義塾大学, 医学部, 講師(非常勤) (90548538)
• Project Period (FY): 2012-04-01 – 2015-03-31
• Keywords: 気圧 / 内耳

Outline of Final Research Achievements

I previously reported that distinct neurons in the vestibular nucleus as well as trigeminal nucleus caudalis responded to lowering barometric pressure by electrophysiological study. I aim to examine whether the vestibular nucleus neurons of conscious rats are affected by lowering barometric pressure(LP).
C-Fos expression was examined in the vestibular nucleus by immunohistochemistry. In LP groups, the number of c-Fos immunoreactive neurons showed a significant increase compared to control groups. The data imply that lowering barometric pressure could affect the vestibular system.

Free Research Field

環境生理学