2014 Fiscal Year Final Research Report
identification of host factors associated with pathogenesis of measles virus
| Project/Area Number |
24790453
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Virology
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| Research Institution | National Institute of Infectious Diseases |
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Principal Investigator |
NAKATSU Yuichiro 国立感染症研究所, ウイルス第三部, 主任研究官 (70572113)
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| Project Period (FY) |
2012-04-01 – 2015-03-31
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| Keywords | 麻疹ウイルス |
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| Outline of Final Research Achievements |
To elucidate the function of measles virus (MV) C protein in pathogenesis, identification of novel factors associated with the C protein in MV-infected cells was performed. As a result, the C protein was associated with MV N and P protein in infected cells. Moreover, the C protein was colocalized with the RNP complex composed of N, P and L protein and genomic RNA and also host recycling endosome in MV-infected cells.
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| Free Research Field |
ウイルス学
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