2013 Fiscal Year Final Research Report
Rapid identification of aminoglycoside resistant bacteria using thiol probe
| Project/Area Number |
24790571
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Laboratory medicine
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| Research Institution | 独立行政法人国立国際医療研究センター |
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Principal Investigator |
ANDO Tomoe (北尾 公英) 独立行政法人国立国際医療研究センター, その他部局等, 研究員 (80462787)
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| Project Period (FY) |
2012-04-01 – 2014-03-31
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| Keywords | 薬剤耐性 / 迅速診断 / アミノグリコシド |
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| Research Abstract |
Emergence of multidrug-resistant (MDR) Pseudomonas aeruginosa is serious problem in the medical setting. Rapid detection system for such bacteria is urgently needed. Recently, epidemiological researches have revealed that most of MDR P. aeruginosa is producing aminoglycoside modifying enzyme to acquire aminoglycoside resistances. In this study, I focused on the mechanism of aminoglycoside modifying enzyme function and aimed to develop a rapid detection system for bacteria producing aminoglycoside modifying enzyme using thiol prove.
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Research Products
(2 results)
