Feasibility study of Volumetric Modulated Arc Therapy for malignant pleural mesothelioma

2014 Fiscal Year Final Research Report

• Project/Area Number: 24791294
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Multi-year Fund
• Research Field: Radiation science
• Research Institution: Yamaguchi University
• Principal Investigator: SHIINOKI Takehiro 山口大学, 医学(系)研究科(研究院), 助教 (30610456)
• Project Period (FY): 2012-04-01 – 2015-03-31
• Keywords: 悪性胸膜中皮腫 / 回転型強度変調放射線治療 / 品質管理法

Outline of Final Research Achievements

The purpose of this study was to perform the feasibility study to introduce the volumetric intensity modulated arc radiotherapy (VMAT) for malignant pleural mesothelioma. The high dose volumes of lung for VMAT (V20 Gy) were lower than those for IMRT. On the other hands, the low dose volume of lung for IMRT (V5 Gy) were higher than those for IMRT. However, radiation treatment time using VMAT is half more than that for IMRT.
We have developed the dose reconstructed methods using the measured dose by 3D detector. For IMRT plan for prostate and pancreas cancer, the developed methods were verified and that was high accuracy for patient specific quality assurance. This developed methods will be very useful for VMAT for malignant pleural mesothelioma.

Free Research Field

医学物理学