2013 Fiscal Year Final Research Report
Role of microRNA in fracture healing and its potentail application
| Project/Area Number |
24791544
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Orthopaedic surgery
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| Research Institution | Kobe University |
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Principal Investigator |
LEE Sang Yang 神戸大学, 医学部附属病院, 特定助教 (40533732)
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| Project Period (FY) |
2012-04-01 – 2014-03-31
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| Keywords | 骨折治癒 / microRNA / 骨再生 / 偽関節 |
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| Research Abstract |
We for the first time showed microRNA expression patterns specific for fracture healing in rats. Our study revealed five microRNAs that remarkably increased and five microRNAs that remarkably decreased in the process of fracture healing. To characterize microRNA profiles in fracture healing is important for understanding the molecular mechanism for fracture healing. This study may provide new evidence for the clinical application of microRNA for enhancement of fracture healing.
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