2014 Fiscal Year Final Research Report
An exploratory investigation of the biomarkers for senescence and arteriosclerosis in renal transplant donors and recipients
| Project/Area Number |
24791653
|
|---|
| Research Category |
Grant-in-Aid for Young Scientists (B)
|
| Allocation Type | Multi-year Fund |
|---|
| Research Field |
Urology
|
|---|
| Research Institution | Kagawa University |
|---|
Principal Investigator |
SOFUE Tadashi 香川大学, 医学部附属病院, 助教 (80452671)
|
|---|
| Project Period (FY) |
2012-04-01 – 2015-03-31
|
| Keywords | 生体腎移植 / マージナルドナー / 高血圧 / 老化 |
|---|
| Outline of Final Research Achievements |
The level of senescence markers P16INK4A and SA-β-GAL in the donated kidney differed between living-kidney donors without proteinuria and kidney dysfunction when patients were classified by the age and presence of hypertension. Therefore, the quality of kidneys from donors based on the criteria of the Amsterdam forum was not uniform. The level of urinary albumin excretion was partially associated with that of senescence markers in the donated kidney.
|
| Free Research Field |
腎移植
|
