Efficacy of two-piece oral appliance therapy for obstructive sleep apnea patients

2015 Fiscal Year Final Research Report

• Project/Area Number: 24792064
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Multi-year Fund
• Research Field: Prosthetic dentistry
• Research Institution: Tokyo Medical and Dental University
• Principal Investigator: Inukai Shusuke 東京医科歯科大学, 医歯(薬)学総合研究科, 助教 (90436650)
• Project Period (FY): 2012-04-01 – 2016-03-31
• Keywords: 睡眠時無呼吸症候群 / 口腔内装置

Outline of Final Research Achievements

We investigated whether it is possible to the predict the therapeutic effect of oral appliance (OA) therapy by using a respiratory airway resistance-measuring instrument used in the field of respiratory medicine, prior to clarifying the therapeutic effect, adverse reactions, and compliance of mobile OA therapy for integrated OA. Integrated optical spectrometry tests were conducted for patients with obstructive sleep apnea (OSA). In our analysis of the correlation between apnea-hypopnea index (AHI) and viscous resistance, we found that the AHI of patients with OSA tended to increase as viscous resistance increased. We also found that the AHI could be easily reduced in patients in whom viscous resistance could be easily reduced with OA therapy. This shows that the therapeutic effect of OA can be predicted on the basis of the rate of improvement in viscous resistance by performing measurements using a forward movement simulator.

Free Research Field

補綴，睡眠歯学