2014 Fiscal Year Final Research Report
Clarification of mechanisms of metastasis suppression centered around DPT, extracellular matrix protein in oral cancer
| Project/Area Number |
24792174
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Surgical dentistry
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| Research Institution | University of Tsukuba |
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Principal Investigator |
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| Project Period (FY) |
2012-04-01 – 2015-03-31
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| Keywords | Dermatopontin / microRNA / 口腔がん |
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| Outline of Final Research Achievements |
Dermatopontin (DPT) which exists extracellular matrix was significantly down-regulated and was indicated its expression related to cancer metastasis. We tried to find out microRNA which controls DPT expression and yields a clue of cancer metastasis. As a result, several kinds of microRNA was picked out in oral cancer, but microRNA which changes DPT expression wasn't seen in those.
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| Free Research Field |
口腔がん
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